Clinical Trial Patient Recruitment Direct Mail.
Enroll faster with a repeatable, accountable direct mail system.
Clinical trials succeed or stall on enrollment. Direct mail is the vehicle for reaching potential participants in the communities around each site without getting lost in the inbox.
Mail reaches households within driving distance of each site, invites a site’s existing patients to learn about studies they may qualify for, and gives every respondent a direct path to prescreening.
Direct One prints, personalizes and mails IRB-approved recruitment materials, with in-house creative, data and analytics teams on the same floor as our presses. One study team approves the campaign. Every site receives its own version, with its own investigator, address, coordinator contact and tracking.
We welcome the RFP process for sponsors, contract research organizations, site networks and patient recruitment agencies seeking a print and mail partner.
Why Direct One?
Recruitment teams answer to two pressures at once: enrollment timelines that cost money with every month of delay, and regulatory requirements that govern every word a participant reads.
Direct One brings commercial printing, mail services, data processing and creative together under one roof, so a campaign moves from approved file to mailbox without handoffs between vendors.
Patient data stays protected under HIPAA-compliant processes and SOC 2-certified controls.
Ready to mail at scale? Talk to our team about leveraging U.S. postage incentives today.
Key Data Points:
Enrollment drives your timeline
Most trials need nearly twice their planned timeline to reach enrollment goals, and 11 percent of activated sites fail to enroll a single patient, according to research from the Tufts Center for the Study of Drug Development. Recruitment that reaches more qualified participants sooner protects the entire study schedule.
One approval for every site
Variable data printing lets a single approved campaign carry site-specific investigators, addresses, maps, coordinator names and phone numbers. Language versions can be produced from the same approved file. Direct One versions, prints and mails for every site in the study, including sites activated mid-enrollment.
Secure and trackable
Patient data is handled under HIPAA-compliant processes in SOC 2-certified systems. Every campaign includes QR codes and personalized URLs that route respondents to prescreening, with results reported by site in Direct One’s online dashboard. Study teams can compare response across every site, and every result is verifiable.
IRB-approved, then printed exactly as approved
Recruitment materials must match the version an institutional review board approved. Direct One manages version control for every protocol, site and amendment, so each mailing carries the approved language and nothing else.
Outreach to a site’s own patients
Many sites hold patient records that identify people who may qualify for a study. Direct One mails these patients under HIPAA-compliant processes, with the authorizations or waivers your IRB requires.
Precision Targeting
Reach households by drive time to each site, age, gender, household composition and self-reported health interest data where permitted. Lists are built to match each protocol’s broad eligibility profile, so mail reaches the people most likely to qualify.